Hemicholinium dibromide

CAS No. 312-45-8

Hemicholinium dibromide( HC3 | HC 3 | HC-3 | Hemicholinium3 | Hemicholinium 3 )

Catalog No. M13999 CAS No. 312-45-8

A potent inhibitor of the high affinity uptake system for CHOLINE. It has less effect on the low affinity uptake system.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 37 In Stock
10MG 59 In Stock
25MG 133 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    Hemicholinium dibromide
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent inhibitor of the high affinity uptake system for CHOLINE. It has less effect on the low affinity uptake system.
  • Description
    A potent inhibitor of the high affinity uptake system for choline. It has less effect on the low affinity uptake system. Since choline is one of the components of acetylcholine, treatment with hemicholinium can deplete acetylcholine from cholinergic terminals. Hemicholinium 3 is commonly used as a research tool in animal and in vitro experiments.
  • In Vitro
    Cell Viability Assay Cell Line:The human small cell lung carcinoma cell line NCI-H69 Concentration:1 mM Incubation Time:Added every day for 2 days. Result:Markedly inhibited cell viability.
  • In Vivo
    ——
  • Synonyms
    HC3 | HC 3 | HC-3 | Hemicholinium3 | Hemicholinium 3
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ChR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    312-45-8
  • Formula Weight
    574.35
  • Molecular Formula
    C24H34Br2N2O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 10 mM
  • SMILES
    OC1(C2=CC=C(C3=CC=C(C4(O)OCC[N+](C)(C)C4)C=C3)C=C2)OCC[N+](C)(C)C1.[Br-].[Br-]
  • Chemical Name
    2,2'-([1,1'-biphenyl]-4,4'-diyl)bis(2-hydroxy-4,4-dimethylmorpholin-4-ium) bromide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Soukup O, et al. Toxicol Lett. 2012 Aug 3;212(3):315-9.
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